Gene and Cell Therapy Lab
directed by Dr.Roger Bumgarner.PhD
http://www.iths.org
a member since 4/29/2011

Contact Info

For information contact
Ponni Anandakumar,M.Sc.

206-598-7038
Institiute of Translational Health Sciences
SS719, University of Washington Medical Center
1959 NE Pacific
Seattle, WA 98195

USA

Services Provided

offers production support to both Academics and Companies.

Misc Services

  • IND submissions
  • Process Development
  • Pre-clinical consultation

Biologics Produced

  • working cell banks
  • Isolated and Expanded T-Cells
  • Hematopoietic Progenitor Cells
  • Hematopoietic Cell Isolations
  • GMP grade FACS sorted cell populations; human embryonic stem cells; human induced pluripotent stem cells; differentiated tissues from these cell types.
  • Gene-modified T-Cells
  • full GMP facility. Master cell banks
  • Antigen Specific T-cells
  • Peptide Loaded Dendritic Cell Tumor Vaccines

Vector Support

  • Retrovirus
  • Lentivirus

About this facility

The Gene and Cell Therapy Core Lab (GCTC) provides translational researchers with the infrastructure, training and technical expertise necessary to develop and manufacture  gene modified cells, vector production and ex-vivo manipulation of cells for novel Gene and Cell Therapy Products.

We facilitate bench –to- bedside translation of gene and cellular therapy research such as immunotherapy and stem cell therapy. We provide both manufacturing and regulatory support needed by clinical research investigators to navigate the challenges of Phase I/II clinical trials. To ensure patient safety and compliance with current Good Manufacturing Practices, we operate under a comprehensive Quality Assurance program.

Facilities:

 The GCTC lab is a 2200 sq.ft clean room facility located on the UW CRC. It has four separate ISO class 7 BL2 suites (with two suites under negative pressure). Each suite is equipped with biosafety cabinets, incubators, centrifuges and refrigerators. It has a CliniMACS® cell selection system for cell enrichment and /or cell depletion. The facility is also equipped with a controlled rate freezer and LN2 vapor storage system. The equipments are continuosly monitored by a validated Reese Centron® monitoring system.